CTLA-4/CD28 Signaling Pathway

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Address:
4D Praed Street
London 11967
England
United Kingdom
Phone number:
16316197922

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CD28 is the best characterized and most effective co-stimulatory molecule expressed by naive and primed T cells. CD28 is a 44-kDa glycoprotein that binds to B7-1 (CD80) and B7-2 (CD86) on antigen-presenting cells (APCs) CD28 might be associate, in its unphosphorylated state, with the serine/threonine protein phosphatase 2A (PP2A).

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